How Often to Take HCG on TRT

If you’re currently on Testosterone Replacement Therapy (TRT) or considering it, you may have come across the term HCG (Human Chorionic Gonadotropin). At Tulsi Wellness Club, we get asked one important question all the time:

“How often should I take HCG while on TRT?”

It’s a smart question—and the answer can significantly impact your hormonal balance, fertility, and long-term health. In this guide, we’ll explain the role of HCG in TRT, the ideal dosing frequency, and how we approach HCG therapy at Tulsi Wellness Club to support your full-spectrum hormone optimization.

What Is HCG and Why Is It Used With TRT?

HCG is a hormone that mimics luteinizing hormone (LH) in the body. LH is naturally produced by your pituitary gland and plays a key role in stimulating the testes to produce testosterone and sperm.

When you begin TRT, especially with exogenous testosterone (like injections), your body often shuts down natural LH production, which in turn suppresses testicular function. This can lead to:

Testicular shrinkage
Reduced sperm production (infertility)
Decreased intratesticular testosterone
Lowered overall sense of vitality

That’s where HCG comes in. It helps maintain testicular activity even while you’re on TRT, which can be crucial for fertility, testicle size, and natural hormone synergy.

How Often Should You Take HCG on TRT?

At Tulsi Wellness Club, we typically recommend HCG injections 2–3 times per week, depending on your personal needs and goals.

Our Standard HCG Protocol:

Dose: 250–500 IU per injection
Frequency: 2 to 3 times per week (e.g., Monday/Thursday or Monday/Wednesday/Friday)

This schedule helps mimic the body’s natural LH pulses, offering stable support for testicular function while minimizing hormonal fluctuations.

Why We Don’t Recommend Weekly HCG Only

While some clinics might prescribe HCG just once weekly for convenience, this method is less effective at maintaining consistent LH-like stimulation. HCG has a relatively short half-life (around 24–36 hours), so spacing out doses ensures steady, reliable effects.

With 2–3x weekly dosing, you’ll notice:

Better preservation of testicular size
Improved sperm production and fertility outcomes
More stable mood and energy
Fewer estrogenic side effects
Enhanced sense of wellbeing

Consistency is key—and that’s why we carefully guide you through your dosing calendar to ensure you're hitting the right schedule.

Do You Need HCG on TRT?

Not everyone on TRT needs HCG, but there are several cases where we strongly recommend it:

You want to preserve fertility

HCG is critical if you plan to conceive children now or in the future. Without it, your sperm production can drop dramatically on TRT.

You want to avoid testicular shrinkage

HCG helps maintain the natural activity of the testes, preventing the testicular atrophy (shrinkage) that some men experience with testosterone alone.

You want to maintain natural testosterone synergy

HCG supports a more physiologic hormonal environment, which many men find results in improved overall energy, libido, and mood.

At Tulsi Wellness Club, we take the time to understand your long-term goals—whether that’s maximizing performance, protecting fertility, or supporting general vitality—and design your TRT + HCG protocol accordingly.

How We Incorporate HCG at Tulsi Wellness Club

We believe in personalized, precision medicine. That means every HCG protocol is built around your labs, goals, and response—not a one-size-fits-all approach.

Here’s what our process typically looks like:

Initial hormone panel – including LH, FSH, testosterone, and estradiol
Discussion of fertility goals – are you planning to conceive in 6 months, 2 years, or not at all?
Customized TRT protocol – including your preferred injection schedule
HCG added when appropriate – either at the start of therapy or phased in
Regular monitoring – we track symptoms and blood levels every 8–12 weeks
Adjustments as needed – we may increase or reduce HCG dose/frequency based on results

This proactive model ensures that you feel your best—without compromising future fertility or hormonal balance.

Are There Any Side Effects of HCG?

When properly dosed, HCG is generally well tolerated, but as with any hormone, some men may experience mild side effects, such as:

Headaches
Bloating or water retention
Increased estrogen levels (especially if overused)
Mood fluctuations

That’s why we emphasize ongoing monitoring and dose management. At Tulsi Wellness Club, we help you avoid these side effects with smart dosing and, if necessary, the addition of an aromatase inhibitor to keep estrogen in check.

Final Thoughts: How Often to Take HCG on TRT

So, how often should you take HCG while on TRT?

At Tulsi Wellness Club, our recommended protocol is 250–500 IU of HCG injected 2–3 times per week. This frequency provides the most effective support for testicular health, fertility preservation, and overall hormone synergy.

We tailor every treatment plan to the individual. Whether you’re looking to preserve fertility, improve mood, or simply maintain hormonal balance while optimizing testosterone, HCG can be a powerful ally—and we’ll show you how to use it effectively.

Ready to Feel Better, Live Better, and Protect Your Long-Term Health?

At Tulsi Wellness Club, we specialize in personalized hormone optimization. We don’t just give you testosterone—we give you a plan, a team, and a strategy that respects your body’s long-term balance.

Book your free consultation today and let’s create a TRT plan—including HCG—that helps you feel your best, now and in the future.